Retinal Imaging

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Clinical and Epidemiologic Research April 2019

Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study

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Caroline Brandl; Christiane Brücklmayer; Felix Günther; Martina E. Zimmermann; Helmut Küchenhoff; Horst Helbig; Bernhard H. F. Weber; Iris M. Heid; Klaus J. Stark
TAGS: sample size, biological response modifiers, color, photoreceptors, reference values, software, diagnostic imaging, eye, age-related macular degeneration, reliability, german, spectral-domain optical coherence tomography, surveys
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1581-1594. doi: 10.1167/iovs.18-25332

Includes: Supplemental Content

Glaucoma April 2019

Discordance of Disc-Fovea Raphe Angles Determined by Optical Coherence Tomography and MP-3 Microperimetry in Eyes With a Glaucomatous Hemifield Defect

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Sotaro Mori; Takuji Kurimoto; Akiyasu Kanamori; Mari Sakamoto; Kaori Ueda; Yuko Yamada-Nakanishi; Makoto Nakamura
TAGS: glaucoma, fovea centralis, eye, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1403-1411. doi: 10.1167/iovs.18-26354

Retina March 2019

Deletion of miR-182 Leads to Retinal Dysfunction in Mice

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Kun-Chao Wu; Xue-Jiao Chen; Guang-Hui Jin; Xiao-Yun Wang; Dan-Dan Yang; Yan-Ping Li; Lue Xiang; Bo-Wen Zhang; Gao-Hui Zhou; Chang-Jun Zhang; Zi-Bing Jin
TAGS: electroretinography, mice, retina, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1265-1274. doi: 10.1167/iovs.18-24166

Includes: Supplemental Content

Genetics March 2019

Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice

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Viola Kretschmer; Sarita Rani Patnaik; Friedrich Kretschmer; Mira Manilal Chawda; Victor Hernandez-Hernandez; Helen Louise May-Simera
TAGS: phenotype, bardet-biedl syndrome, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1132-1143. doi: 10.1167/iovs.18-25210

Includes: Supplemental Content

Retina March 2019

Three-Dimensional Adaptive Optics–Assisted Visualization of Photoreceptors in Healthy and Pathologically Aged Eyes

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Adrian Reumueller; Ursula Schmidt-Erfurth; Matthias Salas; Stefan Sacu; Wolfgang Drexler; Michael Pircher; Andreas Pollreisz
TAGS: drusen, face, optics, photoreceptors, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1144-1155. doi: 10.1167/iovs.18-25702

Anatomy and Pathology/Oncology March 2019

Rabbit Model of Intra-Arterial Chemotherapy Toxicity Demonstrates Retinopathy and Vasculopathy Related to Drug and Dose, Not Procedure or Approach

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Anthony B. Daniels; Michael T. Froehler; Amy H. Nunnally; Janene M. Pierce; Ivan Bozic; Cameron A. Stone; Pranav R. Santapuram; Yuankai K. Tao; Kelli L. Boyd; Lauren E. Himmel; Sheau-chiann Chen; Liping Du; Debra L. Friedman; Ann Richmond
TAGS: vascular diseases, melphalan, oryctolagus cuniculus, retinal diseases, eye, toxic effect, toxicity due to chemotherapy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):954-964. doi: 10.1167/iovs.18-25346

Biochemistry and Molecular Biology March 2019

Electrophysiological Changes During Early Steps of Retinitis Pigmentosa

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Ulisse Bocchero; Beatrice M. Tam; Colette N. Chiu; Vincent Torre; Orson L. Moritz
TAGS: animals, transgenic, darkness, electroretinography, photons, phototransduction, retinitis pigmentosa, rhodopsin, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):933-943. doi: 10.1167/iovs.18-25347

Includes: Supplemental Content

Glaucoma February 2019

Factors Influencing Optical Coherence Tomography Peripapillary Choroidal Thickness: A Multicenter Study

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Hongli Yang; Haomin Luo; Stuart K. Gardiner; Christy Hardin; Glen P. Sharpe; Joseph Caprioli; Shaban Demirel; Christopher A. Girkin; Jeffrey M. Liebmann; Christian Y. Mardin; Harry A. Quigley; Alexander F. Scheuerle; Brad Fortune; Balwantray C. Chauhan; Claude F. Burgoyne
TAGS: ethnic group, multicenter studies, optic disk, eye, sclera, optical coherence tomography, american society of clinical oncology
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):795-806. doi: 10.1167/iovs.18-25407

Includes: Supplemental Content

Retina February 2019

Age-Related Alterations in Retinal Tissue Perfusion and Volumetric Vessel Density

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Ying Lin; Hong Jiang; Yi Liu; Giovana Rosa Gameiro; Giovanni Gregori; Chuanhui Dong; Tatjana Rundek; Jianhua Wang
TAGS: aging, vascular flow, perfusion, body tissue, retina, volume, retinal nerve fiber layer, tissue perfusion
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):685-693. doi: 10.1167/iovs.18-25864

Glaucoma February 2019

Changes in Optic Nerve Head Vessel Density After Acute Primary Angle Closure Episode

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Sasan Moghimi; Mona SafiZadeh; Masoud Aghsaei Fard; Nazgol Motamed-Gorji; Nassim Khatibi; Rebecca Chen; Robert N. Weinreb
TAGS: glaucoma, eye, retinal nerve fiber layer, optic disk, angiogram
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):552-558. doi: 10.1167/iovs.18-25915

Visual Psychophysics and Physiological Optics February 2019

Healthy Aging Impairs Photon Absorption Efficiency of Cones

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Daphné Silvestre; Angelo Arleo; Rémy Allard
TAGS: aging, process of absorption, retinal cone, contrast sensitivity, lens (device), optics, photons, noise, elderly, young adult, luminance, healthy aging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):544-551. doi: 10.1167/iovs.18-25598

Retina January 2019

Do Müller Cells Act as Optical Fibers in the Primate Retina?

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Kuno Kirschfeld
TAGS: optics, photoreceptors, primates, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):345-348. doi: 10.1167/iovs.18-25831

Visual Neuroscience January 2019

The Effect of Atropine on Human Global Flash mfERG Responses to Retinal Defocus

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Safal Khanal; Philip R. K. Turnbull; Nicholas Lee; John R. Phillips
TAGS: atropine
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):218-225. doi: 10.1167/iovs.18-24600

Visual Neuroscience January 2019

Retinal Deficits Precede Cognitive and Motor Deficits in a Rat Model of Type II Diabetes

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Rachael S. Allen; Andrew Feola; Cara T. Motz; Amy L. Ottensmeyer; Kyle C. Chesler; Ryan Dunn; Peter M. Thulé; Machelle T. Pardue
TAGS: diabetes mellitus, type 2, retina, exploratory behavior, rats, hyperglycemia, diabetes mellitus, motor deficits, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):123-133. doi: 10.1167/iovs.18-25110

Visual Neuroscience January 2019

Cone Photoreceptor Dysfunction in Early-Stage Diabetic Retinopathy: Association Between the Activation Phase of Cone Phototransduction and the Flicker Electroretinogram

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J. Jason McAnany; Jason C. Park
TAGS: photopsia, diabetic retinopathy, diabetes mellitus, pathophysiology, phototransduction, electroretinography, retinal cone, nonproliferative diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):64-72. doi: 10.1167/iovs.18-25946

Retina January 2019

Analysis of Retinal Segmentation Changes at High Altitude With and Without Acetazolamide

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Alexander Kenneth Clarke; Mariano Cozzi; Christopher Henry Ernest Imray; Alex Wright; Sergio Pagliarini; for the Birmingham Medical Research Expeditionary Society
TAGS: retinal nerve fiber layer, high altitude, acetazolamide
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):36-40. doi: 10.1167/iovs.18-24966

Retina December 2018

A Novel Achromatopsia Mouse Model Resulting From a Naturally Occurring Missense Change in Cngb3

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Mark M. Hassall; Alun R. Barnard; Harry O. Orlans; Michelle E. McClements; Peter Charbel Issa; Sher A. Aslam; Robert E. MacLaren
TAGS: mice, retinal cone, mutation, electroretinography, achromatopsia
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6102-6110. doi: 10.1167/iovs.18-24328

Visual Neuroscience December 2018

Effect of Stimulus Intensity and Visual Field Location on Rod- and Cone-Mediated Pupil Response to Focal Light Stimuli

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Soad Haj Yahia; Amit Hamburg; Ifat Sher; Daniel Ben Ner; Saeed Yassin; Ron Chibel; Michael Mimouni; Estela Derazne; Michael Belkin; Ygal Rotenstreich
TAGS: retinal cone, visual fields, pupil reaction, pupil, rod photoreceptors, blue light
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):6027-6035. doi: 10.1167/iovs.18-23767

Includes: Supplemental Content

Retina December 2018

OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy

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Jia Qin; Nicholas Rinella; Qinqin Zhang; Hao Zhou; Jessica Wong; Michael Deiner; Austin Roorda; Travis C. Porco; Ruikang K. Wang; Daniel M. Schwartz; Jacque L. Duncan
TAGS: angiogram, atrophy, optics, diagnostic imaging, eye, chief complaint, retinal cone, fluid flow, perfusion
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5985-5992. doi: 10.1167/iovs.18-25032

Includes: Supplemental Content

Retinal Cell Biology December 2018

Mitochondrial Respiration in Outer Retina Contributes to Light-Evoked Increase in Hydration In Vivo

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Bruce A. Berkowitz; Robert H. Podolsky; Haohua Qian; Yichao Li; Ke Jiang; Jacob Nellissery; Anand Swaroop; Robin Roberts
TAGS: magnetic resonance imaging, respiration, mitochondria, mice, inbred c57bl, diagnostic imaging, mice, retina, water, diffusion magnetic resonance imaging, magnetic resonance cholangiography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5957-5964. doi: 10.1167/iovs.18-25682

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Retinal Layer Thicknesses in Early Age-Related Macular Degeneration: Results From the German AugUR Study

Discordance of Disc-Fovea Raphe Angles Determined by Optical Coherence Tomography and MP-3 Microperimetry in Eyes With a Glaucomatous Hemifield Defect

Deletion of miR-182 Leads to Retinal Dysfunction in Mice

Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice

Three-Dimensional Adaptive Optics–Assisted Visualization of Photoreceptors in Healthy and Pathologically Aged Eyes

Rabbit Model of Intra-Arterial Chemotherapy Toxicity Demonstrates Retinopathy and Vasculopathy Related to Drug and Dose, Not Procedure or Approach

Electrophysiological Changes During Early Steps of Retinitis Pigmentosa

Factors Influencing Optical Coherence Tomography Peripapillary Choroidal Thickness: A Multicenter Study

Age-Related Alterations in Retinal Tissue Perfusion and Volumetric Vessel Density

Changes in Optic Nerve Head Vessel Density After Acute Primary Angle Closure Episode

Healthy Aging Impairs Photon Absorption Efficiency of Cones

Do Müller Cells Act as Optical Fibers in the Primate Retina?

The Effect of Atropine on Human Global Flash mfERG Responses to Retinal Defocus

Retinal Deficits Precede Cognitive and Motor Deficits in a Rat Model of Type II Diabetes

Cone Photoreceptor Dysfunction in Early-Stage Diabetic Retinopathy: Association Between the Activation Phase of Cone Phototransduction and the Flicker Electroretinogram

Analysis of Retinal Segmentation Changes at High Altitude With and Without Acetazolamide

A Novel Achromatopsia Mouse Model Resulting From a Naturally Occurring Missense Change in Cngb3

Effect of Stimulus Intensity and Visual Field Location on Rod- and Cone-Mediated Pupil Response to Focal Light Stimuli

OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy

Mitochondrial Respiration in Outer Retina Contributes to Light-Evoked Increase in Hydration In Vivo

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