Surgery

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Cornea April 2025

Antigen Presentation by Extracellular Vesicles in the Acute Phase of Corneal Transplantation

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Toshiki Shimizu; Takahiko Hayashi; Junki Kurita; Kentaro Yuda; Nobuhisa Mizuki; Satoru Yamagami
TAGS: antigen processing and presentation, extracellular vesicles, keratoplasty, tissue transplants, cornea
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):38. https://doi.org/10.1167/iovs.66.4.38

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics April 2025

The Relationship Between Binocular Imbalance and Myopic Shift in Unoperated Eyes After Unilateral SMILE and tPRK

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Kaiyan Huang; Mi Xia; Qianwen Gong; Kexin Li; Yijie Xu; Hui Wang; Yuzhou Wang; Jiawei Zhou; Liang Hu
TAGS: eye, imbalance, spatial frequency
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):32. https://doi.org/10.1167/iovs.66.4.32

Includes: Supplemental Content

Lens April 2025

Elevated Inflammatory Cytokines Persist in the Aqueous Humor Years After Cataract Surgery

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Caili Hao; Emily Fan; Zongbo Wei; Kazi Rafsan Radeen; Neha Purohit; Kailin Li; Sharad Purohit; Xingjun Fan
TAGS: cataract, cataract surgery, chronic inflammation, cytokine, hypertension, surgical procedures, operative, aqueous humor, surgery specialty, donors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):12. https://doi.org/10.1167/iovs.66.4.12

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology March 2025

One-Month-Old Rabbits Exhibit a Longer Postoperative Remodeling in Extraocular Muscles Compared to 3-Month-Old Rabbits

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Jiangtao Lou; Hailu Huang; Yiyi Peng; Chunxiao Wang; Meiping Xu; Xinping Yu
TAGS: muscle of orbit, oryctolagus cuniculus, postoperative care, surgical procedures, operative, embryo, russell-silver syndrome, surgery specialty, somatostatin receptor scintigraphy, preoperative care
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):12. https://doi.org/10.1167/iovs.66.3.12

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2025

Peripheral Refraction and Axial Growth Rate After Multifocal or Monofocal Intraocular Lens Implantation in Chinese Pediatric Cataract Patients

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Qiuxuan Du; Ying Zhang; Yusen Huang
TAGS: cataract, cataract, childhood, chinese (other dialects), chinese people, eye, growth rate, intraocular lens implantation procedure, multifocal intraocular lenses, refraction, surgical procedures, operative
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):33. https://doi.org/10.1167/iovs.66.2.33

Cornea February 2025

Modeling Neuropathic Corneal Pain: Pulled Nerve Approach With Elevated Krt16 Gene Expression

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Mohd. Afzal Khan; Gehan Fatima; Acquah Emmanuel; Sang Seong Kim; Hyuk Sang Kwon; Kyung Chul Yoon; Young Ro Kim; Euiheon Chung
TAGS: cornea, gene expression, neurons, pain, surgical procedures, operative
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):35. https://doi.org/10.1167/iovs.66.2.35

Includes: Supplemental Content

Cornea February 2025

Senolytic Treatment Alleviates Corneal Allograft Rejection Through Upregulation of Angiotensin-Converting Enzyme 2 (ACE2)

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Hao Chi; Li Ma; Fanxing Zeng; Xiaolei Wang; Peng Peng; Xiaofei Bai; Ting Zhang; Wenhui Yin; Yaoyao Yu; Lingling Yang; Qingjun Zhou; Chao Wei; Weiyun Shi
TAGS: aging, allografting, angiotensin converting enzyme 2, cornea, keratoplasty, navitoclax, rejection (psychology), senolytics, stress, transplant rejection
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):15. https://doi.org/10.1167/iovs.66.2.15

Includes: Supplemental Content

Glaucoma January 2025

Artificial Intelligence in Predicting Ocular Hypertension After Descemet Membrane Endothelial Keratoplasty

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Min Seok Kim; Heesuk Kim; Hyung Keun Lee; Chan Yun Kim; Wungrak Choi
TAGS: artificial intelligence, descemet's membrane endothelial keratoplasty, ocular hypertension, survival analysis, preoperative care, risk factors, tissue transplants, glaucoma, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):61. https://doi.org/10.1167/iovs.66.1.61

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2025

The Value of Orbital Exenteration for Eyelid Sebaceous Carcinoma in Stages II to IV: A Cohort Study of 78 Patients

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Jie Chen; Tianyu Zhu; Ziyue Huang; Renbing Jia; Shiqiong Xu
TAGS: cohort studies, eye, orbit evisceration, sebaceous adenocarcinoma, sebaceous adenocarcinoma of eyelid, neoplasm metastasis, surgical procedures, operative, recurrence, selenocysteine, cerebral arterial thrombosis
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):40. https://doi.org/10.1167/iovs.66.1.40

Includes: Supplemental Content

Lens January 2025

Aqueous Proteomic and Metabolomic Profiles in Low-Energy vs High-Energy Femtosecond Laser-Assisted Cataract Surgery

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Chang Liu; Xinyue Wang; Hon Shing Ong; Marcus Ang; Soon-Phaik Chee; Jianhong Ching; Kee Voon Chua; Sharon Hong Yu Han; Jodhbir S. Mehta; Lei Zhou; Yu-Chi Liu
TAGS: cataract surgery, lasers, metabolomics, proteins, proteomics, metabolites
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):10. https://doi.org/10.1167/iovs.66.1.10

Includes: Supplemental Content

Retina December 2024

Epiretinal Membrane: Correlations Among Clinical, Immunohistochemical, and Biochemical Features and Their Prognostic Implications

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Hyun Seung Yang; Suho Choi; Soojin Kim; Chan Hong Min; Dongwoo Kim; Youngseop Lee; Minji Kim; Donghoon Koo; Jaiyoung Ryu; Jeongmin Kim
TAGS: body tissue, cytokine, epiretinal membrane, patient prognosis, postoperative care, preoperative care, prognostic factors, surgical procedures, operative, n-cadherins, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):25. https://doi.org/10.1167/iovs.65.14.25

Lens December 2024

Mefunidone Inhibits Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in Lens Epithelial Cells

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Cong Fan; Yu Yang; Mengling You; Zhuo Chen; Jian Jiang
TAGS: epithelial to mesenchymal transition, inflammation, lens epithelial cell, oxidative stress, surgical procedures, operative, western blotting, mitogen-activated protein kinases, fluorescent antibody technique
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):17. https://doi.org/10.1167/iovs.65.14.17

Includes: Supplemental Content

Cornea November 2024

Determining the Relationship Between Corneal Stiffening and Tissue Dehydration After Corneal Cross-Linking

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Raymundo Rodríguez-López; Joshua N. Webb; Metecan Erdi; Peter Kofinas; Walfre Franco; Hongyuan Zhang; James Bradley Randleman; Giuliano Scarcelli
TAGS: body tissue, cornea, corneal collagen cross-linking, cross-linking, dehydration, dehydration of tissue specimen
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):14. https://doi.org/10.1167/iovs.65.13.14

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology October 2024

Accommodative and Vergence Responses to a Moving Stimulus in Concussion

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Jennifer X. Haensel; Sophia Marusic; Kristin E. Slinger; Carissa H. Wu; Neerali Vyas; Christabel A. Ameyaw Baah; Amber Hu; Joellen Leonen; Caitlyn Y. Lew; Gayathri Srinivasan; Amir Norouzpour; Erin Jenewein; Siva Meiyeppen; Mitchell Scheiman; Aparna Raghuram; Tawna L. Roberts
TAGS: brain concussion, visual accommodation, dog, domestic
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):45. https://doi.org/10.1167/iovs.65.12.45

Retina October 2024

Temporal Changes in the Retinal Pigment Epithelium–Bruch's Membrane Complex Thickness After Autologous Retinal Transplantation in Myopic Eyes

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Shohei Kitahata; Tatsuya Inoue; Shin Tanaka; Jacob Y. H. Chin; Satoru Shinoda; Maiko Maruyama-Inoue; Kazuaki Kadonosono
TAGS: bruch's basal membrane, edema, eye, retinal pigment epithelium, retinal transplantation, transplantation, autologous, tissue transplants, surgical procedures, operative, postoperative care
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):25. https://doi.org/10.1167/iovs.65.12.25

Visual Neuroscience September 2024

Delayed Surgical Reversal of Optic Nerve Compression Leads to Exponential Degeneration of Optic Nerve Fibers and Selective Sparing of the Small Fibers

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XiaoHui Jiang; Boyue Xu; Shuang Yao; Zhuowei Wang; Mingyue Liu; Yikui Zhang; Wencan Wu; Ende Wu
TAGS: axon, decompression, external, decompressive incision, optic nerve, optic nerve compression, optic nerve decompression, surgical procedures, operative, tissue degeneration, survival, apoptosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):40. https://doi.org/10.1167/iovs.65.11.40

Retina September 2024

Changes in Intrinsically Photosensitive Retinal Ganglion Cells, Dopaminergic Amacrine Cells, and Their Connectivity in the Retinas of Lid Suture Myopia

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Ying Ling; Yao Wang; Jingjing Ye; Changlin Luan; Ailing Bi; Yu Gu; Xuefeng Shi
TAGS: dopamine, eye, myopia, retina, sutures, amacrine cells, retinal ganglion cells, vesicular monoamine transporter 2, melanopsin, pituitary adenylate cyclase activating polypeptide
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):8. https://doi.org/10.1167/iovs.65.11.8

Includes: Supplemental Content

Glaucoma September 2024

Long-Term Changes in Lamina Cribrosa Curvature Index After Trabeculectomy in Glaucomatous Eyes

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Xiao Shang; Nathanael Urs Häner; Joel-Benjamin Lincke; Valentin Pfeiffer; Pascal Aurel Gubser; Martin Sebastian Zinkernagel; Jan Darius Unterlauft
TAGS: cribriform plate, eye, glaucoma, intraocular pressure, trabeculectomy, preoperative care
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):3. https://doi.org/10.1167/iovs.65.11.3

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology August 2024

Binocular Visual Deficits at Low to High Spatial Frequency in Intermittent Exotropia After Surgery

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Xi Yu; Lili Wei; Yiya Chen; Hanyi Zhang; Huanyun Yu; Jiawei Zhou; Meiping Xu
TAGS: imbalance, intermittent exotropia, spatial frequency, surgical procedures, operative, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):41. https://doi.org/10.1167/iovs.65.10.41

Retina August 2024

Wound Healing in a Porcine Model of Retinal Holes

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Madeline Evers Olufsen; Jens Hannibal; Nina Buus Sørensen; Anders Tolstrup Christiansen; Ulrik Christensen; Grazia Pertile; David H. Steel; Steffen Heegaard; Jens Folke Kiilgaard
TAGS: retinal perforations, suidae, wound healing, surgical procedures, operative, follow-up
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):35. https://doi.org/10.1167/iovs.65.10.35

Includes: Supplemental Content

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Antigen Presentation by Extracellular Vesicles in the Acute Phase of Corneal Transplantation

The Relationship Between Binocular Imbalance and Myopic Shift in Unoperated Eyes After Unilateral SMILE and tPRK

Elevated Inflammatory Cytokines Persist in the Aqueous Humor Years After Cataract Surgery

One-Month-Old Rabbits Exhibit a Longer Postoperative Remodeling in Extraocular Muscles Compared to 3-Month-Old Rabbits

Peripheral Refraction and Axial Growth Rate After Multifocal or Monofocal Intraocular Lens Implantation in Chinese Pediatric Cataract Patients

Modeling Neuropathic Corneal Pain: Pulled Nerve Approach With Elevated Krt16 Gene Expression

Senolytic Treatment Alleviates Corneal Allograft Rejection Through Upregulation of Angiotensin-Converting Enzyme 2 (ACE2)

Artificial Intelligence in Predicting Ocular Hypertension After Descemet Membrane Endothelial Keratoplasty

The Value of Orbital Exenteration for Eyelid Sebaceous Carcinoma in Stages II to IV: A Cohort Study of 78 Patients

Aqueous Proteomic and Metabolomic Profiles in Low-Energy vs High-Energy Femtosecond Laser-Assisted Cataract Surgery

Epiretinal Membrane: Correlations Among Clinical, Immunohistochemical, and Biochemical Features and Their Prognostic Implications

Mefunidone Inhibits Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in Lens Epithelial Cells

Determining the Relationship Between Corneal Stiffening and Tissue Dehydration After Corneal Cross-Linking

Accommodative and Vergence Responses to a Moving Stimulus in Concussion

Temporal Changes in the Retinal Pigment Epithelium–Bruch's Membrane Complex Thickness After Autologous Retinal Transplantation in Myopic Eyes

Delayed Surgical Reversal of Optic Nerve Compression Leads to Exponential Degeneration of Optic Nerve Fibers and Selective Sparing of the Small Fibers

Changes in Intrinsically Photosensitive Retinal Ganglion Cells, Dopaminergic Amacrine Cells, and Their Connectivity in the Retinas of Lid Suture Myopia

Long-Term Changes in Lamina Cribrosa Curvature Index After Trabeculectomy in Glaucomatous Eyes

Binocular Visual Deficits at Low to High Spatial Frequency in Intermittent Exotropia After Surgery

Wound Healing in a Porcine Model of Retinal Holes

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