Visual Neuroscience

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Retinal Cell Biology September 2021

The Role of the Wnt Pathway in VEGF/Anti-VEGF-Dependent Control of the Endothelial Cell Barrier

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Yueru Li; Basma Baccouche; Olamide Olayinka; Anara Serikbaeva; Andrius Kazlauskas
TAGS: endothelial cells, permeability, vascular endothelial growth factor a, anti-vascular endothelial growth factor therapy, endothelium, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):17. doi: https://doi.org/10.1167/iovs.62.12.17

Includes: Supplemental Content

Glaucoma September 2021

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression

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Yuri Fujino; Ryo Asaoka; Hiroshi Murata; Takehiro Yamashita
TAGS: central retinal artery, glaucoma, intraocular pressure, optic disk, retina, visual fields, maximum tolerated dose
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):6. doi: https://doi.org/10.1167/iovs.62.12.6

Multidisciplinary Ophthalmic Imaging August 2021

Diffusion Tensor Imaging of Visual Pathway Abnormalities in Five Glaucoma Animal Models

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Max K. Colbert; Leon C. Ho; Yolandi van der Merwe; Xiaoling Yang; Gillian J. McLellan; Samuel A. Hurley; Aaron S. Field; Hongmin Yun; Yiqin Du; Ian P. Conner; Carlos Parra; Muneeb A. Faiq; John H. Fingert; Gadi Wollstein; Joel S. Schuman; Kevin C. Chan
TAGS: animal model, glaucoma, visual pathways, diffusion tensor imaging
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):21. doi: https://doi.org/10.1167/iovs.62.10.21

Retina August 2021

Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma

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Linya Li; Shaoqing He; Yang Liu; Thomas Yorio; Dorette Z. Ellis
TAGS: caspase-3, glaucoma, mice, optic nerve, pentazocine, retinal ganglion cells, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):17. doi: https://doi.org/10.1167/iovs.62.10.17

Glaucoma August 2021

Comparison of Optic Nerve Head Microvasculature Between Normal-Tension Glaucoma and Nonarteritic Anterior Ischemic Optic Neuropathy

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Ji-Ah Kim; Eun Ji Lee; Tae-Woo Kim; Hee Kyung Yang; Jeong-Min Hwang
TAGS: low tension glaucoma, microvascular network, nonarteritic anterior ischemic optic neuropathy, optic disk, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):15. doi: https://doi.org/10.1167/iovs.62.10.15

Includes: Supplemental Content

Glaucoma August 2021

Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression

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Heather M. Schmitt; Rachel L. Fehrman; Margaret E. Maes; Huan Yang; Lian-Wang Guo; Cassandra L. Schlamp; Heather R. Pelzel; Robert W. Nickells
TAGS: apoptosis, disease susceptibility, immunohistochemistry, mice, neurons, plasmids, signal transduction, proteins, caspase-3, histone deacetylase
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):14. doi: https://doi.org/10.1167/iovs.62.10.14

Includes: Supplemental Content

Retina August 2021

Retinal Responses to Simulated Optical Blur Using a Novel Dead Leaves ERG Stimulus

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Athanasios Panorgias; Stephanie Aigbe; Emily Jeong; Carles Otero; Peter J. Bex; Fuensanta A. Vera-Diaz
TAGS: electroretinography, optics, photon correlation spectroscopy
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):1. doi: https://doi.org/10.1167/iovs.62.10.1

Includes: Supplemental Content

Retinal Cell Biology July 2021

Optic Nerve Engraftment of Neural Stem Cells

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Jiun L. Do; Salam Allahwerdy; Ryan Caezar C. David; Robert N. Weinreb; Mark H. Tuszynski; Derek S. Welsbie
TAGS: neural stem cells, optic nerve, axon
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):30. doi: https://doi.org/10.1167/iovs.62.9.30

Retina July 2021

Activated Blood Coagulation Factor X (FXa) Contributes to the Development of Traumatic PVR Through Promoting RPE Epithelial-Mesenchymal Transition

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Han Han; Xiao Zhao; Mengyu Liao; Yinting Song; Caiyun You; Xue Dong; Xueli Yang; Xiaohong Wang; Bo Huang; Mei Du; Hua Yan
TAGS: epithelial to mesenchymal transition, eye, factor x, fibrosis, mice, ocular trauma, oryctolagus cuniculus, receptor, par-1, retinal pigment cell, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):29. doi: https://doi.org/10.1167/iovs.62.9.29

Includes: Supplemental Content

Glaucoma July 2021

Longitudinal In Vivo Changes in Retinal Ganglion Cell Dendritic Morphology After Acute and Chronic Optic Nerve Injury

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Delaney C. M. Henderson; Jayme R. Vianna; John Gobran; Johnny Di Pierdomenico; Michele L. Hooper; Spring R. M. Farrell; Balwantray C. Chauhan
TAGS: dendrites, diagnostic imaging, ganglia, glaucoma, language morphology, mice, morphology, optic nerve, optic nerve injuries, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):5. doi: https://doi.org/10.1167/iovs.62.9.5

Clinical and Epidemiologic Research July 2021

Environmental and Nutritional Determinants of Macular Pigment in a Mexican Population

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Marina Green-Gomez; Rachel Moran; James Stringham; Cesar Hernández-Alcaraz; Kenny Mendoza-Herrera; J. Jans Fromow-Guerra; Alfonso Prado-Cabrero; John Nolan
TAGS: carotenoids, diet, macular pigment, mexico
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):18. doi: https://doi.org/10.1167/iovs.62.9.18

Multidisciplinary Ophthalmic Imaging July 2021

Evaluation of the Effect of a Novel β3 -Adrenergic Agonist on Choroidal Vascularity

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Murat Topcuoğlu; Fatih Aslan
TAGS: agonists, mirabegron
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):17. doi: https://doi.org/10.1167/iovs.62.9.17

Visual Neuroscience July 2021

Responses of Postreceptoral Pathways Elicited by L- and M-Cone Isolating ON- and OFF-Electroretinograms in Glaucoma Patients

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Avinash J. Aher; Folkert K. Horn; Cord Huchzermeyer; Robert Lämmer; Jan Kremers
TAGS: electroretinography, glaucoma, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):14. doi: https://doi.org/10.1167/iovs.62.9.14

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology July 2021

Protective Role of Limitrin in Experimental Autoimmune Optic Neuritis

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Bo Young Chun; Jong-Heon Kim; Youn-Kwan Jung; Yoon Seok Choi; Gunwoo Kim; Tomoko Yonezawa; Kyoungho Suk
TAGS: astrocytes, autoimmunity, mice, optic nerve, optic neuritis, plasma
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):8. doi: https://doi.org/10.1167/iovs.62.9.8

Includes: Supplemental Content

Genetics June 2021

Characterization of the Spectrum of Ophthalmic Changes in Patients With Alagille Syndrome

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Mariana Matioli da Palma; Austin D. Igelman; Cristy Ku; Amanda Burr; Jia Yue You; Emily M. Place; Nan-Kai Wang; Jin Kyun Oh; Kari E. Branham; Xinxin Zhang; Jeeyun Ahn; Michael B. Gorin; Byron L. Lam; Cecinio C. Ronquillo; Paul S. Bernstein; Aaron Nagiel; Rachel Huckfeldt; Michelle T. Cabrera; John P. Kelly; Benjamin Bakall; Alessandro Iannaccone; Robert B. Hufnagel; Wadih M. Zein; Robert K. Koenekoop; David G. Birch; Paul Yang; Abigail T. Fahim; Mark E. Pennesi
TAGS: arteriohepatic dysplasia, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):27. doi: https://doi.org/10.1167/iovs.62.7.27

Includes: Supplemental Content

Visual Neuroscience June 2021

Synaptosomal Actin Dynamics in the Developmental Visual Cortex Regulate Behavioral Visual Acuity in Rats

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Ai-Ling Bi; Yue-Ying Zhang; Zhi-Yuan Lu; Hong-Ying Tang; Xiu-Yan Zhang; Zi-Han Zhang; Bo-Qin Li; Da-Dong Guo; Sheng Gong; Qian Li; Xing-Rong Wang; Xiu-Zhen Lu; Hong-Sheng Bi
TAGS: actins, rats, visual acuity, visual cortex, mitochondria, primary visual cortex
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):20. doi: https://doi.org/10.1167/iovs.62.7.20

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2021

Age-Related Retinal Changes in Wild-Type C57BL/6J Mice Between 2 and 32 Months

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Salma Ferdous; Kristie L. Liao; Isabelle D. Gefke; Vivian R. Summers; Wenfei Wu; Kevin J. Donaldson; Yong-Kyu Kim; Jana T. Sellers; Jendayi A. Dixon; Debresha A. Shelton; Shanu Markand; Somin M. Kim; Nan Zhang; Jeffrey H. Boatright; John M. Nickerson
TAGS: eye, mice, mice, inbred c57bl, body weight, photoreceptors, aging, retina
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):9. doi: https://doi.org/10.1167/iovs.62.7.9

Includes: Supplemental Content

Retinal Cell Biology June 2021

Sigma 1 Receptor Modulates Optic Nerve Head Astrocyte Reactivity

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Jing Zhao; Graydon Gonsalvez; Manuela Bartoli; Barbara A. Mysona; Sylvia B. Smith; Kathryn E. Bollinger
TAGS: astrocytes, glial fibrillary acidic protein, optic disk, receptors, sigma, mice, stress, ischemia, cell culture techniques
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):5. doi: https://doi.org/10.1167/iovs.62.7.5

Visual Neuroscience June 2021

Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype

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Mengjuan Wu; Qinqin Deng; Xinlan Lei; Yuxin Du; Yin Shen
TAGS: abdominal compartment syndrome, acute coronary syndromes, amacrine cells, american cancer society, american college of surgeons, electroretinography, mice, retina, ablation, rna
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):1. doi: https://doi.org/10.1167/iovs.62.7.1

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology May 2021

Inhibition of Retinal Ganglion Cell Loss By a Novel ROCK Inhibitor (E212) in Ischemic Optic Nerve Injury Via Antioxidative and Anti-Inflammatory Actions

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Yao-Tseng Wen; Ching-Wen Huang; Chih-Peng Liu; Chih-Hung Chen; Chia-Mu Tu; Chrong-Shiong Hwang; Yi-Hsun Chen; Wan-Ru Chen; Keh-Liang Lin; Yu-Chieh Ho; Ta-Ching Chen; Rong-Kung Tsai
TAGS: anti-inflammatory agents, infarction, ischemia, neuroprotective effect, optic nerve injuries, painful bladder syndrome, retina, retinal ganglion cells, macrophages, fluoro-gold
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):21. doi: https://doi.org/10.1167/iovs.62.6.21

Includes: Supplemental Content

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The Role of the Wnt Pathway in VEGF/Anti-VEGF-Dependent Control of the Endothelial Cell Barrier

The Relationship Between Optic Disc and Retinal Artery Position and Glaucomatous Visual Field Progression

Diffusion Tensor Imaging of Visual Pathway Abnormalities in Five Glaucoma Animal Models

Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma

Comparison of Optic Nerve Head Microvasculature Between Normal-Tension Glaucoma and Nonarteritic Anterior Ischemic Optic Neuropathy

Increased Susceptibility and Intrinsic Apoptotic Signaling in Neurons by Induced HDAC3 Expression

Retinal Responses to Simulated Optical Blur Using a Novel Dead Leaves ERG Stimulus

Optic Nerve Engraftment of Neural Stem Cells

Activated Blood Coagulation Factor X (FXa) Contributes to the Development of Traumatic PVR Through Promoting RPE Epithelial-Mesenchymal Transition

Longitudinal In Vivo Changes in Retinal Ganglion Cell Dendritic Morphology After Acute and Chronic Optic Nerve Injury

Environmental and Nutritional Determinants of Macular Pigment in a Mexican Population

Evaluation of the Effect of a Novel β3 -Adrenergic Agonist on Choroidal Vascularity

Responses of Postreceptoral Pathways Elicited by L- and M-Cone Isolating ON- and OFF-Electroretinograms in Glaucoma Patients

Protective Role of Limitrin in Experimental Autoimmune Optic Neuritis

Characterization of the Spectrum of Ophthalmic Changes in Patients With Alagille Syndrome

Synaptosomal Actin Dynamics in the Developmental Visual Cortex Regulate Behavioral Visual Acuity in Rats

Age-Related Retinal Changes in Wild-Type C57BL/6J Mice Between 2 and 32 Months

Sigma 1 Receptor Modulates Optic Nerve Head Astrocyte Reactivity

Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype

Inhibition of Retinal Ganglion Cell Loss By a Novel ROCK Inhibitor (E212) in Ischemic Optic Nerve Injury Via Antioxidative and Anti-Inflammatory Actions

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