Visual Neuroscience

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Biochemistry and Molecular Biology June 2021

Age-Related Retinal Changes in Wild-Type C57BL/6J Mice Between 2 and 32 Months

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Salma Ferdous; Kristie L. Liao; Isabelle D. Gefke; Vivian R. Summers; Wenfei Wu; Kevin J. Donaldson; Yong-Kyu Kim; Jana T. Sellers; Jendayi A. Dixon; Debresha A. Shelton; Shanu Markand; Somin M. Kim; Nan Zhang; Jeffrey H. Boatright; John M. Nickerson
TAGS: eye, mice, mice, inbred c57bl, body weight, photoreceptors, aging, retina
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):9. doi: https://doi.org/10.1167/iovs.62.7.9

Includes: Supplemental Content

Retinal Cell Biology June 2021

Sigma 1 Receptor Modulates Optic Nerve Head Astrocyte Reactivity

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Jing Zhao; Graydon Gonsalvez; Manuela Bartoli; Barbara A. Mysona; Sylvia B. Smith; Kathryn E. Bollinger
TAGS: astrocytes, glial fibrillary acidic protein, optic disk, receptors, sigma, mice, stress, ischemia, cell culture techniques
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):5. doi: https://doi.org/10.1167/iovs.62.7.5

Visual Neuroscience June 2021

Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype

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Mengjuan Wu; Qinqin Deng; Xinlan Lei; Yuxin Du; Yin Shen
TAGS: abdominal compartment syndrome, acute coronary syndromes, amacrine cells, american cancer society, american college of surgeons, electroretinography, mice, retina, ablation, rna
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):1. doi: https://doi.org/10.1167/iovs.62.7.1

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology May 2021

Inhibition of Retinal Ganglion Cell Loss By a Novel ROCK Inhibitor (E212) in Ischemic Optic Nerve Injury Via Antioxidative and Anti-Inflammatory Actions

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Yao-Tseng Wen; Ching-Wen Huang; Chih-Peng Liu; Chih-Hung Chen; Chia-Mu Tu; Chrong-Shiong Hwang; Yi-Hsun Chen; Wan-Ru Chen; Keh-Liang Lin; Yu-Chieh Ho; Ta-Ching Chen; Rong-Kung Tsai
TAGS: anti-inflammatory agents, infarction, ischemia, neuroprotective effect, optic nerve injuries, painful bladder syndrome, retina, retinal ganglion cells, macrophages, fluoro-gold
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):21. doi: https://doi.org/10.1167/iovs.62.6.21

Includes: Supplemental Content

Cornea May 2021

Transcriptomic and Immunohistochemical Analysis of Progressive Keratoconus Reveal Altered WNT10A in Epithelium and Bowman's Layer

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James W. Foster; Rupin N. Parikh; Jiangxia Wang; Kraig S. Bower; Mario Matthaei; Shukti Chakravarti; Albert S. Jun; Charles G. Eberhart; Uri S. Soiberman
TAGS: epithelium, keratoconus, wnt10a gene, bowman's layer
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):16. doi: https://doi.org/10.1167/iovs.62.6.16

Includes: Supplemental Content

Glaucoma May 2021

Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells

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Bindu Kodati; Dorota L. Stankowska; Vignesh R. Krishnamoorthy; Raghu R. Krishnamoorthy
TAGS: endothelin-1, glaucoma, mice, nerve degeneration, neuroprotection, phosphotransferases, retinal ganglion cells, immunohistochemistry, intravitreal injections
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):13. doi: https://doi.org/10.1167/iovs.62.6.13

Genetics May 2021

Expanding the FDXR -Associated Disease Phenotype: Retinal Dystrophy Is a Recurrent Ocular Feature

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Neringa Jurkute; Priya D. Shanmugarajah; Marios Hadjivassiliou; Jenny Higgs; Miodrag Vojcic; Iain Horrocks; Yann Nadjar; Valerie Touitou; Guy Lenaers; Roy Poh; James Acheson; Anthony G. Robson; F. Lucy Raymond; Mary M. Reilly; Patrick Yu-Wai-Man; Anthony T. Moore; Andrew R. Webster; Gavin Arno; for the Genomics England Research Consortium
TAGS: family, optic atrophy, phenotype, recurrence, retinal dystrophies
Invest. Ophthalmol. Vis. Sci.. 2021; 62(6):2. doi: https://doi.org/10.1167/iovs.62.6.2

Includes: Supplemental Content

Visual Neuroscience April 2021

Correlations Between Dark-Adapted Rod Threshold Elevations and ERG Response Deficits in Duchenne Muscular Dystrophy

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Mirella Telles Salgueiro Barboni; Sarah Leonardo Dias; Leonardo Aparecido Silva; Francisco Max Damico; Kallene Summer Vidal; Marcelo Fernandes Costa; Balázs Vince Nagy; Jan Kremers; Dora Fix Ventura
TAGS: duchenne's muscular dystrophy, electroretinography, rod photoreceptors, dark adaptation, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):29. doi: https://doi.org/10.1167/iovs.62.4.29

Includes: Supplemental Content

Glaucoma April 2021

Posture-Dependent Collapse of the Optic Nerve Subarachnoid Space: A Combined MRI and Modeling Study

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Petter Holmlund; Karen-Helene Støverud; Anders Wåhlin; Urban Wiklund; Jan Malm; Gauti Jóhannesson; Anders Eklund
TAGS: magnetic resonance imaging, optic nerve, posture, subarachnoid space
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):26. doi: https://doi.org/10.1167/iovs.62.4.26

Includes: Supplemental Content

Anatomy and Pathology/Oncology April 2021

Coadministration With Carbidopa Enhances the Antimyopic Effects of Levodopa in Chickens

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Kate Thomson; Ian Morgan; Tamsin Kelly; Cindy Karouta; Regan Ashby
TAGS: carbidopa, levodopa, dopamine, myopia
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):25. doi: https://doi.org/10.1167/iovs.62.4.25

Includes: Supplemental Content

Visual Neuroscience April 2021

Light Environment Influences Developmental Programming of the Metabolic and Visual Systems in Mice

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Danielle A. Clarkson-Townsend; Katie L. Bales; Carmen J. Marsit; Machelle T. Pardue
TAGS: body weight, circadian rhythm disorders, mice, visual system, blood glucose, vision, glucose tolerance, weight (force), electroretinography
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):22. doi: https://doi.org/10.1167/iovs.62.4.22

Includes: Supplemental Content

Retinal Cell Biology April 2021

Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors

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Yi Chen; Binxin Wu; Jian Feng He; Jingyao Chen; Zi Wei Kang; Dandan Liu; Junjie Luo; Kexin Fang; Xiaoxu Leng; Haibin Tian; Jingying Xu; Caixia Jin; Jieping Zhang; Juan Wang; Jingfa Zhang; Qingjian Ou; Lixia Lu; Furong Gao; Guo-Tong Xu
TAGS: epithelial to mesenchymal transition, retinal pigment cell, signal transduction inhibitor, primary eosinophilic endomyocardial cardiomyopathy
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):21. doi: https://doi.org/10.1167/iovs.62.4.21

Includes: Supplemental Content

Glaucoma April 2021

Racial Differences in the Rate of Change in Anterior Lamina Cribrosa Surface Depth in the African Descent and Glaucoma Evaluation Study

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Christopher A. Girkin; Akram Belghith; Christopher Bowd; Felipe A. Medeiros; Robert N. Weinreb; Jeffrey M. Liebmann; James A. Proudfoot; Linda M. Zangwill; Massimo A. Fazio
TAGS: cribriform plate, glaucoma, optic disk, racial differences
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):12. doi: https://doi.org/10.1167/iovs.62.4.12

Includes: Supplemental Content

Visual Neuroscience April 2021

Ocular Dominance and Functional Asymmetry in Visual Attention Networks

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Sinan Liu; Bingyang Zhao; Chaoqun Shi; Xuying Ma; Bernhard A. Sabel; Xiping Chen; Luyang Tao
TAGS: attention, eye, ocular dominance, visual attention
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):9. doi: https://doi.org/10.1167/iovs.62.4.9

Includes: Supplemental Content

Glaucoma April 2021

Longitudinal Observation of Border Tissue Configuration During Axial Elongation in Childhood

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Yong Woo Kim; Jin Ju Choi; Michael J. A. Girard; Jean Martial Mari; Dong Gyu Choi; Ki Ho Park
TAGS: body tissue, child, eye, nose
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):10. doi: https://doi.org/10.1167/iovs.62.4.10

Includes: Multimedia, Supplemental Content

Visual Neuroscience March 2021

Altered Visual Function in a Larval Zebrafish Knockout of Neurodevelopmental Risk Gene pdzk1

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Jiaheng Xie; Patricia R. Jusuf; Bang V. Bui; Stefanie Dudczig; Tamar E. Sztal; Patrick T. Goodbourn
TAGS: electroretinography, genes, genetics, larva, spatial frequency, vision, zebrafish, serotonin, depression, post-stroke, persistent speech disorders
Invest. Ophthalmol. Vis. Sci.. 2021; 62(3):29. doi: https://doi.org/10.1167/iovs.62.3.29

Includes: Supplemental Content

Visual Neuroscience March 2021

Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness

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Juliette Varin; Nassima Bouzidi; Miguel Miranda De Sousa Dias; Thomas Pugliese; Christelle Michiels; Camille Robert; Melissa Desrosiers; José-Alain Sahel; Isabelle Audo; Deniz Dalkara; Christina Zeitz
TAGS: biopharmaceutics classification system, dendrites, electroretinography, mice, night blindness, congenital stationary, proteins, retina
Invest. Ophthalmol. Vis. Sci.. 2021; 62(3):24. doi: https://doi.org/10.1167/iovs.62.3.24

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics March 2021

Binocular Enhancement of Multisensory Temporal Perception

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Collins Opoku-Baah; Mark T. Wallace
TAGS: epidemiologic causality, noise, perception, time perception, total body water, eye, judgment
Invest. Ophthalmol. Vis. Sci.. 2021; 62(3):7. doi: https://doi.org/10.1167/iovs.62.3.7

Multidisciplinary Ophthalmic Imaging February 2021

Follow-Up of Nonarteritic Anterior Ischemic Optic Neuropathy With Optical Coherence Tomography Angiography

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Edouard Augstburger; Arnaud Ballino; Chafik Keilani; Mathieu Robin; Christophe Baudouin; Antoine Labbé
TAGS: angiogram, follow-up, nonarteritic anterior ischemic optic neuropathy, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):42. doi: https://doi.org/10.1167/iovs.62.4.42

Genetics February 2021

Retinal Phenotyping of Ferrochelatase Mutant Mice Reveals Protoporphyrin Accumulation and Reduced Neovascular Response

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S. P. B. Sardar Pasha; Trupti Shetty; Nathan A. Lambert-Cheatham; Kamakshi Sishtla; Deepa Mathew; Anbukkarasi Muniyandi; Neeta Patwari; Ashay D. Bhatwadekar; Timothy W. Corson
TAGS: ferrochelatase, mice, protoporphyrins
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):36. doi: https://doi.org/10.1167/iovs.62.2.36

Includes: Supplemental Content

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Age-Related Retinal Changes in Wild-Type C57BL/6J Mice Between 2 and 32 Months

Sigma 1 Receptor Modulates Optic Nerve Head Astrocyte Reactivity

Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype

Inhibition of Retinal Ganglion Cell Loss By a Novel ROCK Inhibitor (E212) in Ischemic Optic Nerve Injury Via Antioxidative and Anti-Inflammatory Actions

Transcriptomic and Immunohistochemical Analysis of Progressive Keratoconus Reveal Altered WNT10A in Epithelium and Bowman's Layer

Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells

Expanding the FDXR -Associated Disease Phenotype: Retinal Dystrophy Is a Recurrent Ocular Feature

Correlations Between Dark-Adapted Rod Threshold Elevations and ERG Response Deficits in Duchenne Muscular Dystrophy

Posture-Dependent Collapse of the Optic Nerve Subarachnoid Space: A Combined MRI and Modeling Study

Coadministration With Carbidopa Enhances the Antimyopic Effects of Levodopa in Chickens

Light Environment Influences Developmental Programming of the Metabolic and Visual Systems in Mice

Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors

Racial Differences in the Rate of Change in Anterior Lamina Cribrosa Surface Depth in the African Descent and Glaucoma Evaluation Study

Ocular Dominance and Functional Asymmetry in Visual Attention Networks

Longitudinal Observation of Border Tissue Configuration During Axial Elongation in Childhood

Altered Visual Function in a Larval Zebrafish Knockout of Neurodevelopmental Risk Gene pdzk1

Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness

Binocular Enhancement of Multisensory Temporal Perception

Follow-Up of Nonarteritic Anterior Ischemic Optic Neuropathy With Optical Coherence Tomography Angiography

Retinal Phenotyping of Ferrochelatase Mutant Mice Reveals Protoporphyrin Accumulation and Reduced Neovascular Response

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