Vitreous Disorders

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Retina July 2022

EGF Receptor Signaling Modulates YAP Activation and Promotes Experimental Proliferative Vitreoretinopathy

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Wei Zhang; Jing Li
TAGS: epidermal growth factor receptors, signal transduction, vitreoretinopathy, proliferative
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):24. doi: https://doi.org/10.1167/iovs.63.8.24

Retina May 2022

Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy

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Yannik Laich; Julian Wolf; Rozina Ida Hajdu; Anja Schlecht; Felicitas Bucher; Laurenz Pauleikhoff; Martin Busch; Gottfried Martin; Henrik Faatz; Saskia Killmer; Bertram Bengsch; Andreas Stahl; Albrecht Lommatzsch; Günther Schlunck; Hansjürgen Agostini; Stefaniya Boneva; Clemens Lange
TAGS: epiretinal membrane, proteins, tissue membrane, transcription, genetic, vitreoretinopathy, proliferative, sequence analysis, rna, diagnostic imaging, body tissue
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):17. doi: https://doi.org/10.1167/iovs.63.5.17

Includes: Supplemental Content

Retina April 2022

FZD4 in a Large Chinese Population With Familial Exudative Vitreoretinopathy: Molecular Characteristics and Clinical Manifestations

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Jinglin Lu; Li Huang; Limei Sun; Songshan Li; Zhaotian Zhang; Zhaoxin Jiang; Jiaqing Li; Xiaoyan Ding
TAGS: chinese (other dialects), familial exudative vitreoretinopathies, mutation, proband, signs and symptoms, phenotype, chinese people, family
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):7. doi: https://doi.org/10.1167/iovs.63.4.7

Immunology and Microbiology March 2022

Deciphering the Molecular Signature of Human Hyalocytes in Relation to Other Innate Immune Cell Populations

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Julian Wolf; Stefaniya Boneva; Dennis-Dominik Rosmus; Hansjürgen Agostini; Günther Schlunck; Peter Wieghofer; Anja Schlecht; Clemens Lange
TAGS: genes, microglia, monocytes, sequence analysis, rna, transcription, genetic, vitreous body, cell separation, body tissue, fluorescence, rna
Invest. Ophthalmol. Vis. Sci.. 2022; 63(3):9. doi: https://doi.org/10.1167/iovs.63.3.9

Includes: Supplemental Content

Retina February 2022

Plasma and Vitreous Metabolomics Profiling of Proliferative Diabetic Retinopathy

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Hanying Wang; Shu Li; Chingyi Wang; Yihan Wang; Junwei Fang; Kun Liu
TAGS: diabetic retinopathy, metabolomics, plasma, proliferative diabetic retinopathy, vitreous body, metabolites
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):17. doi: https://doi.org/10.1167/iovs.63.2.17

Includes: Supplemental Content

Immunology and Microbiology February 2022

Study of the Correlation Between Severity of Endophthalmitis and Posterior Vitreous Detachment Using a Rabbit Endophthalmitis Model

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Ryo Baba; Kazuhiko Umazume; Naohito Koike; Hiroshi Goto
TAGS: endophthalmitis, oryctolagus cuniculus, vitreous detachment, histopathology tests, retina, eye, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):6. doi: https://doi.org/10.1167/iovs.63.2.6

Retina December 2021

Progression Patterns of Myopic Traction Maculopathy in the Fellow Eye After Pars Plana Vitrectomy of the Primary Eye

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Kangjie Kong; Sisi Xu; Yingchao Wang; Yuhe Qi; Qing Chang; Rui Jiang; Chunhui Jiang; Xin Huang; Dekang Gan; Yanqiong Zhang; Ling Chen; Ling Wang; Xiaogang Luo; Yaowu Qin; Haixiang Wu; Min Zhou; Yingqin Ni; Gezhi Xu
TAGS: eye, macular disorders, traction, vitrectomy, pars plana
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):9. doi: https://doi.org/10.1167/iovs.62.15.9

Genetics December 2021

Ocular Features and Mutation Spectrum of Patients With Familial Exudative Vitreoretinopathy

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Tianchang Tao; Ningda Xu; Jiarui Li; Hongyan Li; Jinfeng Qu; Hong Yin; Jianhong Liang; Mingwei Zhao; Xiaoxin Li; Lvzhen Huang
TAGS: familial exudative vitreoretinopathies, genes, mutation, phenotype, genotype
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):4. doi: https://doi.org/10.1167/iovs.62.15.4

Includes: Supplemental Content

Anatomy and Pathology/Oncology November 2021

Intravitreal HDAC Inhibitor Belinostat Effectively Eradicates Vitreous Seeds Without Retinal Toxicity In Vivo in a Rabbit Retinoblastoma Model

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Jessica V. Kaczmarek; Carley M. Bogan; Janene M. Pierce; Yuankai K. Tao; Sheau-Chiann Chen; Qi Liu; Xiao Liu; Kelli L. Boyd; M. Wade Calcutt; Thomas M. Bridges; Craig W. Lindsley; Debra L. Friedman; Ann Richmond; Anthony B. Daniels
TAGS: belinostat, oryctolagus cuniculus, vitreous body, retinoblastoma, melphalan, seeds, eye
Invest. Ophthalmol. Vis. Sci.. 2021; 62(14):8. doi: https://doi.org/10.1167/iovs.62.14.8

Includes: Supplemental Content

Anatomy and Pathology/Oncology October 2021

Posterior Vitreous Detachment in Normal Healthy Subjects Younger Than Age Twenty

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Ayumi Hayashi; Yoko Ito; Yuki Takatsudo; Naoto Hara; Peter L. Gehlbach; Keisuke Mori
TAGS: eye, vitreous body, vitreous detachment, diagnostic imaging, retina
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):19. doi: https://doi.org/10.1167/iovs.62.13.19

Retina October 2021

Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1 + Macrophage Infiltration

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Iori Wada; Shintaro Nakao; Muneo Yamaguchi; Yoshihiro Kaizu; Mitsuru Arima; Shinichiro Sawa; Koh-Hei Sonoda
TAGS: diabetic retinopathy, lymphangiogenesis, lymphatic vessels, macrophages, mice, protein overexpression, retina, vascular endothelial growth factor a, vascular endothelial growth factor c, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2021; 62(13):17. doi: https://doi.org/10.1167/iovs.62.13.17

Includes: Supplemental Content

Retina September 2021

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

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Yinting Song; Mengyu Liao; Xiao Zhao; Han Han; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: macrophages, massively-parallel genome sequencing, mucopolysaccharidoses, retinal pigment cell, vitreous body, cell-derived microparticles, vitreoretinopathy, proliferative
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):26. doi: https://doi.org/10.1167/iovs.62.12.26

Includes: Supplemental Content

Visual Neuroscience September 2021

The Role of Dopamine in Emmetropization Modulated by Wavelength and Temporal Frequency in Guinea Pigs

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Tian Tian; Leilei Zou; Shu Wang; Rui Liu; Hong Liu
TAGS: 3,4-dihydroxyphenylacetic acid, caviidae, dopamine, vitreous body, cues, blue light, white light, green light
Invest. Ophthalmol. Vis. Sci.. 2021; 62(12):20. doi: https://doi.org/10.1167/iovs.62.12.20

Retina August 2021

En Face Optical Coherence Tomography Imaging of Foveal Dots in Eyes With Posterior Vitreous Detachment or Internal Limiting Membrane Peeling

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Cameron Pole; Adrian Au; Eduardo Navajas; K. Bailey Freund; Srinivas Sadda; David Sarraf
TAGS: diagnostic imaging, eye, face, fovea centralis, optical coherence tomography, tissue membrane, vitreous detachment
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):5. doi: https://doi.org/10.1167/iovs.62.10.5

Retina July 2021

CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy

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Ahmed M. Abu El-Asrar; Mohd Imtiaz Nawaz; Ajmal Ahmad; Mohammad Mairaj Siddiquei; Eef Allegaert; Priscilla W. Gikandi; Gert De Hertogh; Ghislain Opdenakker
TAGS: angiogenesis, biological markers, diabetes mellitus, endothelial cells, enzyme-linked immunosorbent assay, inflammation, proliferative diabetic retinopathy, rats, retina, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):32. doi: https://doi.org/10.1167/iovs.62.9.32

Retina July 2021

Activated Blood Coagulation Factor X (FXa) Contributes to the Development of Traumatic PVR Through Promoting RPE Epithelial-Mesenchymal Transition

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Han Han; Xiao Zhao; Mengyu Liao; Yinting Song; Caiyun You; Xue Dong; Xueli Yang; Xiaohong Wang; Bo Huang; Mei Du; Hua Yan
TAGS: epithelial to mesenchymal transition, eye, factor x, fibrosis, mice, ocular trauma, oryctolagus cuniculus, receptor, par-1, retinal pigment cell, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2021; 62(9):29. doi: https://doi.org/10.1167/iovs.62.9.29

Includes: Supplemental Content

Retina June 2021

Association of Aberrant Posterior Vitreous Detachment and Pathologic Tractional Forces With Myopic Macular Degeneration

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Kai Yuan Tey; Qiu Ying Wong; Yee Shan Dan; Andrew S. H. Tsai; Daniel S. W. Ting; Marcus Ang; Gemmy Chiu Ming Cheung; Shu Yen Lee; Tien Yin Wong; Quan V. Hoang; Chee Wai Wong
TAGS: eye, myopic macular degeneration, staphyloma, vitreous detachment, traction, medication therapy management, macular disorders, prevalence
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):7. doi: https://doi.org/10.1167/iovs.62.7.7

Retina April 2021

Volumetric Optical Imaging and Quantitative Analysis of Age-Related Changes in Anterior Human Vitreous

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Daniel Ruminski; J. Sebag; Raúl Duarte Toledo; Alfonso Jiménez-Villar; Jan K. Nowak; Silvestre Manzanera; Pablo Artal; Ireneusz Grulkowski
TAGS: optical imaging, vitreous body, eye, lens, crystalline, reflex, vestibulo-ocular, diagnostic imaging, contrast sensitivity, veno-occlusive disease
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):31. doi: https://doi.org/10.1167/iovs.62.4.31

Immunology and Microbiology February 2021

Characterization of Gene Therapy Associated Uveitis Following Intravitreal Adeno-Associated Virus Injection in Mice

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Gayathri Tummala; Adam Crain; Jessica Rowlan; Kathryn L. Pepple
TAGS: adeno-associated virus, eye, gene therapy, inflammation, injections, intravitreal injections, mice, uveitis, spatial vectors, flow cytometry
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):41. doi: https://doi.org/10.1167/iovs.62.2.41

Includes: Supplemental Content

Physiology and Pharmacology February 2021

Retinal Aquaporin-4 and Regulation of Water Inflow Into the Vitreous Body

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Satoshi Ueki; Yuji Suzuki; Hironaka Igarashi
TAGS: regulation, vitreous body, water, water channels, mice, magnetic resonance imaging
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):24. doi: https://doi.org/10.1167/iovs.62.2.24

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EGF Receptor Signaling Modulates YAP Activation and Promotes Experimental Proliferative Vitreoretinopathy

Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy

FZD4 in a Large Chinese Population With Familial Exudative Vitreoretinopathy: Molecular Characteristics and Clinical Manifestations

Deciphering the Molecular Signature of Human Hyalocytes in Relation to Other Innate Immune Cell Populations

Plasma and Vitreous Metabolomics Profiling of Proliferative Diabetic Retinopathy

Study of the Correlation Between Severity of Endophthalmitis and Posterior Vitreous Detachment Using a Rabbit Endophthalmitis Model

Progression Patterns of Myopic Traction Maculopathy in the Fellow Eye After Pars Plana Vitrectomy of the Primary Eye

Ocular Features and Mutation Spectrum of Patients With Familial Exudative Vitreoretinopathy

Intravitreal HDAC Inhibitor Belinostat Effectively Eradicates Vitreous Seeds Without Retinal Toxicity In Vivo in a Rabbit Retinoblastoma Model

Posterior Vitreous Detachment in Normal Healthy Subjects Younger Than Age Twenty

Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1 + Macrophage Infiltration

Vitreous M2 Macrophage-Derived Microparticles Promote RPE Cell Proliferation and Migration in Traumatic Proliferative Vitreoretinopathy

The Role of Dopamine in Emmetropization Modulated by Wavelength and Temporal Frequency in Guinea Pigs

En Face Optical Coherence Tomography Imaging of Foveal Dots in Eyes With Posterior Vitreous Detachment or Internal Limiting Membrane Peeling

CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy

Activated Blood Coagulation Factor X (FXa) Contributes to the Development of Traumatic PVR Through Promoting RPE Epithelial-Mesenchymal Transition

Association of Aberrant Posterior Vitreous Detachment and Pathologic Tractional Forces With Myopic Macular Degeneration

Volumetric Optical Imaging and Quantitative Analysis of Age-Related Changes in Anterior Human Vitreous

Characterization of Gene Therapy Associated Uveitis Following Intravitreal Adeno-Associated Virus Injection in Mice

Retinal Aquaporin-4 and Regulation of Water Inflow Into the Vitreous Body

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