Vol. 60, No. 3
Issue cover caption

MRI images were taken in 2015 from patient with Donnai Barrow syndrome (https://www.omim.org/clinicalSynopsis/222448). They were 5 years of age and had an axial length in the right eye 37.71mm and left eye 37.61mm. Retinoscopy showed myopia of approximately R-34.00D and L -35.00D.

Background image shows differential retinal gene expression (red shows upregulated genes; green shows down-regulated genes) in retinas experimentally exposed to either imposed hyperopic (left) or myopic (right) defocus. Adapted from Tkatchenko, Troilo, Benavente, and Tkatchenko, 2018, PLOS Biology; https://doi.org/10.1371/journal.pbio.2006021.


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